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Figure 3: Represents the best six identified ligands from virtual screening and their interactions with the TGFBR2 receptor kinase domain. The ligands 1, 2, 4, and 6 interact with Asp397 of the DFG motif for selective binding to the kinase domain of TGFBR2 and ligands 3 and 5 interact with Asp397 for selective binding and Lys277 at ATP binding site |
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